Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 19/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 18/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011101 | 0.95 | CHRM2 (0.56) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5006030 | 0.90 | CHRM3 (0.57) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5011263 | 0.88 | CHRM3 (0.54) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5009306 | 0.85 | CHRM3 (0.44) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5007030 | 0.83 | CHRM3 (0.41) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5005987 | 0.81 | CHRM3 (0.43) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2835104 | 0.78 | CHRM2 (0.76) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2816830 | 0.78 | CHRM3 (0.76) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2830629 | 0.77 | CHRM2 (0.67) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2816167 | 0.76 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461336-B1 | 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARMA SPA (IT) | 2013-05-22 | — | — | EP | disclosed |
| EP-1918277-A2 | Azulene compounds | Industrial Technology Research Institute (TW) | 2008-05-07 | — | — | EP | disclosed |