Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993292 | 0.93 | MEN1 (0.60) | KMT2AMEN1ESR1ESR2PLA2G4B | |
| SCHEMBL3814114 | 0.90 | ESR1 (0.52) | KMT2AMEN1ESR1ESR2PLA2G4B | |
| SCHEMBL3817761 | 0.88 | MEN1 (0.66) | KMT2AMEN1ESR1ESR2CYP19A1 | |
| SCHEMBL5011891 | 0.86 | ESR1 (0.53) | KMT2AMEN1ESR1ESR2CYP19A1 | |
| SCHEMBL4667623 | 0.85 | ESR1 (0.52) | ESR1ESR2PTGS2POLBTHRA | |
| SCHEMBL3819030 | 0.84 | ESR1 (0.49) | KMT2AMEN1ESR1ESR2PLA2G4B | |
| SCHEMBL3818064 | 0.84 | ESR1 (0.56) | ESR1ESR2CYP19A1PTGS2THRA | |
| SCHEMBL5010212 | 0.84 | ESR1 (0.50) | ESR1ESR2CYP19A1PTGS2THRA | |
| SCHEMBL4665805 | 0.83 | ESR1 (0.60) | KMT2AMEN1ESR1ESR2CYP19A1 | |
| SCHEMBL5007980 | 0.83 | ESR1 (0.49) | ESR1ESR2CYP19A1PTGS2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-12-25 | — | — | US | disclosed |
| US-20080319078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-12-25 | — | — | US | disclosed |
| US-20080319078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | GPER1, ESR2, ESRRG | KMT2A 1969/4885MEN1 3392/4885ESR1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.