SCHEMBL500728

SCHEMBL500728

O=C(O)C=C(C=Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.63
HDAC4 P56524 2/20 0.63
HDAC1 Q13547 2/20 0.63
HDAC2 Q92769 2/20 0.63
HDAC8 Q9BY41 2/20 0.63
HDAC6 Q9UBN7 2/20 0.63
TNKS O95271 1/20 0.63
HCAR2 Q8TDS4 1/20 0.63
HDAC7 Q8WUI4 1/20 0.63
HDAC10 Q969S8 1/20 0.63
HDAC11 Q96DB2 1/20 0.63
TNKS2 Q9H2K2 1/20 0.63
HDAC9 Q9UKV0 1/20 0.63
HDAC5 Q9UQL6 1/20 0.63
MAPT P10636 4/20 0.57
LMNA P02545 3/20 0.57
ALDH1A1 P00352 3/20 0.57
PLIN1 O60240 2/20 0.57
RECQL P46063 2/20 0.57
PLIN5 Q00G26 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355034 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL29833146 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC2HDAC8
Ammonia Solution, Strong SCHEMBL5466710 0.98 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC2HDAC8
Ammonia Solution, Strong SCHEMBL30095494 0.98 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC2HDAC8
Fumaric Acid SCHEMBL6873743 0.96 HDAC3 (0.64) HDAC3HDAC4HDAC1HDAC2HDAC8
Acetic Acid SCHEMBL30239972 0.94 GLA (0.58) HDAC3HDAC4HDAC1HDAC2HDAC8
Acrylic Acid SCHEMBL9718438 0.93 HDAC3 (0.55) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL29832924 0.89 HDAC3 (0.55) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL29441329 0.89 HDAC3 (0.55) HDAC3HDAC4HDAC1HDAC2HDAC8
Styrene SCHEMBL29714786 0.88 HDAC3 (0.55) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290812-A Method for preparing porous biodegradable microspheres based on Click reaction and application 江苏集萃聚合新材料有限公司 2024-07-05 CN claimed
US-20240174989-A1 METHOD FOR PURIFYING PROTEIN DERIVED FROM MEMBRANE PROTEIN COMPLEX SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-05-30 US claimed
EP-4200370-B1 HEAT STABLE INKJET INKS SUN CHEMICAL BV (NL) 2024-05-29 EP claimed
US-20240166904-A1 Water-based Polymeric Colorant Inks for Cellulosic Substrates SUN CHEMICAL CORPORATION (US) 2024-05-23 US claimed
US-11945959-B2 Water-based pigment inks for textiles SUN CHEMICAL CORPORATION (US) 2024-04-02 US claimed
EP-4324839-A1 METHOD FOR PURIFYING PROTEIN DERIVED FROM MEMBRANE PROTEIN COMPLEX Sumitomo Rubber Industries, Ltd. (JP) 2024-02-21 EP claimed
US-20240034893-A1 HEAT STABLE INKJET INKS SUN CHEMICAL CORPORATION (US) 2024-02-01 US claimed
EP-3913022-B1 ANCHOR COAT AGENT SAKATA INX CORP (JP) 2024-01-17 EP claimed
CN-117143558-B High-specific gravity high-weather-resistance ultraviolet deep-curing adhesive and preparation method thereof 信泰永合(烟台)新材料有限公司 2023-12-26 CN claimed
EP-4284881-A1 WATER-BASED POLYMERIC COLORANT INKS Sun Chemical Corporation (US) 2023-12-06 EP claimed
US-20030213410-A1 Combining, a pigment having attached at least one nucleophilic group, at least one polymer containing a carboxylic acid group or salt and a coupling agent CABOT CORPORATION 2003-11-20 US claimed
WO-2003095568-A1 MODIFIED PIGMENTS, PROCESS FOR PREPARING MODIFIED PIGMENTS AND INK COMPOSITIONS CONTAINING THEM CABOT CORPORATION (US) 2003-11-20 WO claimed
US-20030205171-A1 Reacting a pigment having a nucleophilic group (e.g., a diazonium or amine group) with a polymer containing carboxylic acid groups or salts and a coupler CABOT CORPORATION 2003-11-06 US claimed
WO-2003087224-A1 THERMOSET COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2003-10-23 WO claimed
US-20020192436-A1 Ink jet recording material and its use AGFA GRAPHICS NV (BE) 2002-12-19 US claimed
EP-1245400-A1 Multilayer ink-jet recording material and its' use Agfa-Gevaert (BE) 2002-10-02 EP claimed
US-5880182-A POLYCARBOXYLATE, SACCHARIDES, HYDROGENATED SACCHARIDES, POLYHYDRIC ALCOHOL ADDUCTS OF SACCHARIDES MBT HOLDING AG (CH) 1999-03-09 US claimed
EP-0650941-B1 Water-reducing admixtures for cementitious compositions SANDOZ LTD (CH) 1997-03-19 EP claimed
EP-0650941-A1 Water-reducing admixtures for cementitious compositions SANDOZ LTD. (CH) 1995-05-03 EP claimed
US-5391452-A Polyester toner and developer compositions XEROX CORPORATION (US) 1995-02-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174989-A1 METHOD FOR PURIFYING PROTEIN DERIVED FROM MEMBRANE PROTEIN COMPLEX VAMP8, VAMP7, MAX HDAC3 4427/4885HDAC4 4426/4885HDAC1 4147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.