Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007686 | 1.00 | TDP1 (0.45) | TDP1ALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL4733227 | 0.87 | SMN1; SMN2 (0.40) | TDP1ALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL5001576 | 0.87 | SMN1; SMN2 (0.40) | TDP1ALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL8160928 | 0.83 | TDP1 (0.47) | TDP1ALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL8160923 | 0.83 | TDP1 (0.47) | TDP1ALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL4733252 | 0.77 | CCNE2 (0.41) | TDP1ALDH1A1PARP1SMN1; SMN2CYP2C19 | |
| SCHEMBL23037380 | 0.76 | TDP1 (0.66) | TDP1ALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL29922789 | 0.72 | PARP1 (0.61) | TDP1ALDH1A1PARP1SMN1; SMN2HDAC8 | |
| SCHEMBL2060236 | 0.72 | PARP1 (0.61) | TDP1ALDH1A1PARP1SMN1; SMN2HDAC8 | |
| SCHEMBL3399705 | 0.71 | HDAC8 (0.54) | TDP1ALDH1A1TSHRHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250739-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-10-16 | — | — | US | disclosed |