Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008755 | 0.74 | TSHR (0.47) | TSHRCYP3A4FFAR3HDAC3HDAC1 | |
| Allyl Butanoate SCHEMBL263508 | 0.74 | — | — | |
| Allyl Butanoate SCHEMBL16372404 | 0.74 | TSHR (0.71) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL6920650 | 0.74 | TSHR (0.44) | TSHRCYP3A4FFAR3HDAC3HDAC1 | |
| SCHEMBL20819805 | 0.73 | TSHR (0.46) | TSHRCYP3A4FFAR3HDAC3HDAC1 | |
| Allyl Butanoate SCHEMBL28209182 | 0.72 | TSHR (0.69) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| Allyl Butanoate SCHEMBL28052527 | 0.69 | TSHR (0.65) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| Allyl Butanoate SCHEMBL8469685 | 0.69 | TSHR (0.65) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| Allyl Butanoate SCHEMBL4955044 | 0.69 | TSHR (0.65) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL4698282 | 0.69 | TSHR (0.50) | TSHRCYP3A4FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963402-A2 | PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES | Johnson and Johnson Vision Care, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| US-20060229423-A1 | Process for the production of monodisperse and narrow disperse monofunctional silicones | JOHNSON & JOHNSON VISION CARE, INC. | 2006-10-12 | — | — | US | claimed |
| WO-2006102050-A2 | PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-09-28 | — | — | WO | claimed |
| EP-1963402-A2 | PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES | Johnson and Johnson Vision Care, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20060229423-A1 | Process for the production of monodisperse and narrow disperse monofunctional silicones | JOHNSON & JOHNSON VISION CARE, INC. | 2006-10-12 | — | — | US | disclosed |
| WO-2006102050-A2 | PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-09-28 | — | — | WO | disclosed |