Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL5009910

C1CO1.OCCOCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.67
MAPK1 P28482 1/20 0.67
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
ALDH1A1 P00352 2/20 0.45
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.40
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.32
TTR P02766 1/20 0.31
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL2066155 0.97 TSHR (0.62) TSHRMAPK1MEN1KMT2APOLB
Triethylene Glycol SCHEMBL28223124 0.97 MEN1 (0.69) TSHRMAPK1MEN1KMT2APOLB
Di(Hydroxyethyl)Ether SCHEMBL5705750 0.91 TSHR (0.56) TSHRMAPK1MEN1KMT2APOLB
Pentaethylene Glycol SCHEMBL7131185 0.88 MEN1 (0.65) TSHRMAPK1MEN1KMT2APOLB
Triethylene Glycol SCHEMBL617399 0.88 MEN1 (0.65) TSHRMAPK1MEN1KMT2APOLB
Tetraethylene Glycol SCHEMBL618122 0.88 MEN1 (0.65) TSHRMAPK1MEN1KMT2APOLB
Di(Hydroxyethyl)Ether SCHEMBL8146129 0.86 TSHR (0.91) TSHRMAPK1MEN1KMT2APOLB
Di(Hydroxyethyl)Ether SCHEMBL28005463 0.86
Di(Hydroxyethyl)Ether SCHEMBL8146128 0.86 TSHR (0.91) TSHRMAPK1MEN1KMT2APOLB
Di(Hydroxyethyl)Ether SCHEMBL5961692 0.85 TSHR (0.56) TSHRMAPK1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110624472-B Emulsifying agent and preparation method and application thereof 重庆威能钻井助剂有限公司 2023-06-20 CN disclosed
CN-113797343-A Treatment of cancer using coenzyme Q10 combination therapy 博格有限责任公司 2021-12-17 CN disclosed
CN-112156097-A Use of vitamin D for preventing or reducing chemotherapy-induced alopecia 博格有限责任公司 2021-01-01 CN disclosed
US-7438926-B2 Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure ALZA CORPORATION (US) 2008-10-21 US disclosed
CN-100421653-C Method for inhibiting decrease in transdermal flux of drug by inhibiting closure of channel ALZA CORP (US) 2008-10-01 CN disclosed
EP-1335711-B1 TRANSDERMAL DEVICE ALZA CORP (US) 2007-07-25 EP disclosed
CN-1473037-A Method for inhibiting decrease in transdermal flux of drug by inhibiting closure of channel 2004-02-04 CN disclosed
US-6620229-B2 Optical recording media; wear resistance FUJI XEROX CO., LTD. (JP) 2003-09-16 US disclosed
EP-1335711-A2 METHODS FOR INHIBITING DECREASE IN TRANSDERMAL DRUG FLUX BY INHIBITION OF PATHWAY CLOSURE Alza Corporation (US) 2003-08-20 EP disclosed
US-20020102292-A1 Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure CORMIER MICHEL (US) 2002-08-01 US disclosed
WO-2002019985-A2 METHODS FOR INHIBITING DECREASE IN TRANSDERMAL DRUG FLUX BY INHIBITION OF PATHWAY CLOSURE ALZA CORPORATION (US) 2002-03-14 WO disclosed
EP-1167471-A2 Ink, image recording process, ink cartridge, recording unit, ink set, crust-preventing method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2002-01-02 EP disclosed
US-6124506-A REACTING AN OLEFIN OXIDE WITH AN ALCOHOL OVER A CATALYST COMPRISING A LAYERED DOUBLE HYDROXIDE (LDH) CLAY WITH ITS LAYERED STRUCTURE INTACT AND HAVING INTERLAMELLAR ANIONS AT LEAST SOME OF WHICH ARE METAL ANIONS OR (POLY)OXOMETALLATE BP CHEMICALS LIMITED (GB) 2000-09-26 US disclosed
US-5264411-A Mixed with bromoxynil or ioxynil or their salts and esters sprayed postemergence MAY & BAKER LIMITED (GB) 1993-11-23 US disclosed
US-5084528-A Polyestercarbonates as foams, plastics, adhesives and coatings THE DOW CHEMICAL COMPANY (US) 1992-01-28 US disclosed
US-4938901-A Process of making a surgical sponge containing an x-ray contrast agent FIRMA CARL FREUDENBERG (DE) 1990-07-03 US disclosed
US-4816529-A ELASTOMERS, FILMS, FOAMS THE DOW CHEMICAL COMPANY (US) 1989-03-28 US disclosed