SCHEMBL5010824

SCHEMBL5010824

C=CC(=O)OC(S)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.43
HPGD P15428 1/20 0.33
ALDH1A1 P00352 4/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936276 0.81
SCHEMBL1284885 0.76 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11746996 0.76 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
Hydrochloric Acid SCHEMBL7508180 0.76 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL25921 0.75
SCHEMBL26841662 0.75 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2727797 0.75 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL31332333 0.75 HCAR2 (0.52) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL28352250 0.74 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1092841 0.74 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018151-A1 PROCESS FOR PREPARING INERT RAFT POLYMERS Universiteit Gent (BE) 2016-05-11 EP disclosed
US-20130096268-A1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIVERSITEIT GENT (BE) 2013-04-18 US disclosed
US-20080262160-A1 Monodisperse Polymers Containing (Alkyl)Acrylic Acid Moieties, Precursors and Methods for Making them and their Applications UNIVERSITEIT GENT (BE) 2008-10-23 US disclosed
EP-1776399-A1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIVERSITEIT GENT (BE) 2007-04-25 EP disclosed
WO-2006002496-A1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIVERSITEIT GENT (BE) 2006-01-12 WO disclosed