Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012158 | 0.86 | KDM4E (0.34) | KDM4EHTTHRH3ALDH1A1RAB9A | |
| SCHEMBL5011042 | 0.86 | KDM4E (0.34) | KDM4EHTTHRH3ALDH1A1RAB9A | |
| SCHEMBL5011046 | 0.86 | KDM4E (0.34) | KDM4EHTTHRH3ALDH1A1RAB9A | |
| SCHEMBL5063593 | 0.84 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5012744 | 0.84 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5010977 | 0.84 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5012206 | 0.84 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5014312 | 0.84 | HRH3 (0.37) | KDM4EHTTHRH3ALDH1A1RAB9A | |
| SCHEMBL5012901 | 0.83 | KDM4E (0.31) | KDM4EHTTALDH1A1 | |
| SCHEMBL5012902 | 0.83 | KDM4E (0.31) | KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |