Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960794 | 1.00 | BDKRB1 (0.71) | BDKRB1CYP3A4 | |
| SCHEMBL4960803 | 1.00 | BDKRB1 (0.71) | BDKRB1CYP3A4 | |
| SCHEMBL4960795 | 1.00 | BDKRB1 (0.71) | BDKRB1CYP3A4 | |
| SCHEMBL5011094 | 1.00 | BDKRB1 (0.71) | BDKRB1CYP3A4 | |
| SCHEMBL4958267 | 0.93 | BDKRB1 (0.73) | BDKRB1CYP3A4 | |
| SCHEMBL4959820 | 0.93 | BDKRB1 (0.73) | BDKRB1CYP3A4 | |
| SCHEMBL4961956 | 0.93 | BDKRB1 (0.73) | BDKRB1CYP3A4 | |
| SCHEMBL4957908 | 0.92 | BDKRB1 (0.74) | BDKRB1CYP3A4 | |
| SCHEMBL4957898 | 0.92 | BDKRB1 (0.74) | BDKRB1CYP3A4 | |
| SCHEMBL4522376 | 0.92 | BDKRB1 (0.74) | BDKRB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878728-A2 | Derivatives of piperazine and higher homologues thereof for the treatment of inflammation-related disorders | Amgen Inc. (US) | 2008-01-16 | — | — | EP | claimed |