Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.59 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.55 |
| ▸ | BAD | Q92934 | 2/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180559 | 0.84 | PPARG (0.65) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL5009209 | 0.81 | PPARG (0.54) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL5011262 | 0.78 | PPARG (0.53) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL3159492 | 0.78 | PPARG (0.61) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL3168073 | 0.77 | PTGDR2 (0.52) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL15157114 | 0.75 | HTR2C (0.57) | PPARGPPARAPPARDFABP4KDM4E | |
| SCHEMBL5009255 | 0.75 | PPARG (0.55) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL5009245 | 0.75 | PPARG (0.52) | PPARGPPARAMCL1BADPPARD | |
| SCHEMBL5011219 | 0.74 | PPARG (1.00) | PPARGPPARAMCL1PPARD | |
| SCHEMBL4239918 | 0.74 | PPARA (0.57) | PPARGPPARAMCL1BADPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-20050124675-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124675-A1 | Indole compounds | PPARG, PPARD, PPARA | PPARG 1/4885PPARA 3/4885MCL1 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.