Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012721 | 1.00 | PTGS1 (0.55) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL6010834 | 0.88 | PTGS1 (0.52) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5535328 | 0.87 | PTGS1 (0.61) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5535340 | 0.87 | PTGS1 (0.61) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5541282 | 0.87 | PTGS1 (0.61) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL2091190 | 0.86 | PTGS1 (0.57) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL2091186 | 0.86 | PTGS1 (0.57) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5546516 | 0.86 | KCNH2 (0.68) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5547591 | 0.86 | KCNH2 (0.68) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5542718 | 0.86 | KCNH2 (0.68) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |