Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455020 | 0.81 | ABL1 (0.37) | EPHX2ABL1KITKDR | |
| SCHEMBL1455508 | 0.78 | EPHX2 (0.46) | EPHX2ABL1KITMAPTMEN1 | |
| SCHEMBL1455403 | 0.74 | EPHX2 (0.46) | EPHX2MEN1KMT2A | |
| SCHEMBL14914206 | 0.65 | EPHX2 (0.58) | EPHX2MAPTMEN1NPC1KMT2A | |
| SCHEMBL21303580 | 0.63 | EPHX2 (0.51) | EPHX2KMT2ADNMT1DNMT3ALMNA | |
| SCHEMBL15160758 | 0.62 | EPHX2 (0.62) | EPHX2NPC1KMT2A | |
| SCHEMBL8366871 | 0.62 | EPHX2 (0.64) | EPHX2NPC1KMT2ALMNAMDM2 | |
| SCHEMBL12071180 | 0.61 | EPHX2 (0.67) | EPHX2MEN1KMT2A | |
| SCHEMBL17247418 | 0.61 | EPHX2 (0.52) | EPHX2KMT2ACTSK | |
| SCHEMBL4499693 | 0.60 | EPHX2 (0.56) | EPHX2MAPTMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |