Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.76 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605778 | 0.93 | CHRM2 (0.83) | CHRM2CA12CA2CA9TSHR | |
| Hydrochloric Acid SCHEMBL5713128 | 0.91 | CHRM2 (0.80) | CHRM2CA12CA2CA9GRIN1 | |
| Hydrochloric Acid SCHEMBL5713119 | 0.91 | CHRM2 (0.80) | CHRM2CA12CA2CA9GRIN1 | |
| Hydrochloric Acid SCHEMBL3665646 | 0.91 | CHRM2 (0.80) | CHRM2CA12CA2CA9GRIN1 | |
| SCHEMBL13159608 | 0.88 | CHRM2 (0.69) | CHRM2SCN8ACA12CA2CA9 | |
| SCHEMBL4913105 | 0.86 | CHRM2 (0.77) | CHRM2SCN8ACA12CA2CA9 | |
| SCHEMBL4912089 | 0.84 | CHRM2 (0.81) | CHRM2CA12CA2TSHRHTT | |
| SCHEMBL4916612 | 0.84 | CHRM2 (0.81) | CHRM2CA12CA2TSHRHTT | |
| SCHEMBL5034679 | 0.84 | CHRM2 (0.81) | CHRM2CA12CA2TSHRHTT | |
| SCHEMBL5769664 | 0.83 | CHRM2 (0.73) | CHRM2SCN8ACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20080295935-A1 | Rubber Composition and Tire | JSR CORPORATION (JP) | 2008-12-04 | — | — | US | disclosed |