Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012669 | 0.89 | ADORA2A (0.80) | ADORA2A | |
| SCHEMBL5013381 | 0.89 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL5012667 | 0.87 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL5013330 | 0.85 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL5550203 | 0.85 | ADORA2A (0.59) | ADORA2A | |
| SCHEMBL5011715 | 0.85 | — | — | |
| SCHEMBL5011670 | 0.85 | ADORA2A (0.69) | ADORA2A | |
| SCHEMBL5012660 | 0.84 | — | — | |
| SCHEMBL5012672 | 0.83 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL3547778 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633756-B1 | A2A ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN IDEC INC (US) | 2008-12-24 | — | — | EP | claimed |