Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015838 | 1.00 | EPHX2 (0.33) | EPHX2CNR1CNR2LSSGNAI3 | |
| SCHEMBL4805338 | 0.90 | EPHX2 (0.33) | EPHX2CNR1CNR2LSSGNAI3 | |
| SCHEMBL4805368 | 0.90 | EPHX2 (0.33) | EPHX2CNR1CNR2LSSGNAI3 | |
| SCHEMBL4803724 | 0.79 | EPHX2 (0.32) | EPHX2LSS | |
| SCHEMBL4803717 | 0.79 | EPHX2 (0.32) | EPHX2LSS | |
| SCHEMBL7210764 | 0.77 | EPHX2 (0.41) | EPHX2LSS | |
| SCHEMBL7209031 | 0.77 | EPHX2 (0.41) | EPHX2LSS | |
| SCHEMBL7210761 | 0.77 | EPHX2 (0.41) | EPHX2LSS | |
| SCHEMBL7209033 | 0.77 | EPHX2 (0.41) | EPHX2LSS | |
| SCHEMBL7207714 | 0.77 | EPHX2 (0.41) | EPHX2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-B1 | AMINOCYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |