Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090218 | 1.00 | PTGS1 (0.59) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL2097952 | 0.98 | PTGS1 (0.61) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL2097953 | 0.98 | PTGS1 (0.61) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL2089499 | 0.95 | PTGS1 (0.64) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL2089496 | 0.95 | PTGS1 (0.64) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL3465895 | 0.90 | PTGS1 (0.58) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL13282035 | 0.88 | KCNH2 (0.65) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL6010817 | 0.87 | KCNH2 (0.56) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL6010803 | 0.86 | KCNH2 (0.63) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL6010760 | 0.86 | PTGS1 (0.63) | PTGS1SLC6A2SLC6A4KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |