Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455364 | 0.92 | EGFR (1.00) | EGFR | |
| SCHEMBL4443490 | 0.91 | EGFR (0.86) | EGFR | |
| SCHEMBL14036848 | 0.90 | EGFR (1.00) | EGFR | |
| SCHEMBL4447196 | 0.90 | EGFR (1.00) | EGFR | |
| SCHEMBL4454332 | 0.90 | EGFR (1.00) | EGFR | |
| SCHEMBL4448511 | 0.90 | EGFR (1.00) | EGFR | |
| SCHEMBL5025413 | 0.87 | EGFR (0.94) | EGFR | |
| SCHEMBL5548535 | 0.86 | EGFR (0.81) | EGFR | |
| SCHEMBL5026742 | 0.86 | EGFR (0.78) | EGFR | |
| SCHEMBL4443379 | 0.86 | EGFR (0.83) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | EP | disclosed |