⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015075 | 0.75 | USP2 (0.31) | — | |
| SCHEMBL18738 | 0.69 | — | — | |
| SCHEMBL11416999 | 0.69 | — | — | |
| SCHEMBL4153225 | 0.69 | — | — | |
| SCHEMBL6273224 | 0.69 | — | — | |
| SCHEMBL24720704 | 0.67 | — | — | |
| SCHEMBL31239245 | 0.67 | CA12 (0.32) | — | |
| SCHEMBL13462484 | 0.67 | — | — | |
| SCHEMBL5013639 | 0.67 | NR1I2 (0.31) | — | |
| SCHEMBL31239246 | 0.67 | CA12 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987314-B2 | Amide, urea or sulfone amide linked benzothiazole inhibitors of endothelial lipase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-24 | — | — | US | disclosed |
| US-20140045811-A1 | AMIDE, UREA OR SULFONE AMIDE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY | 2014-02-13 | — | — | US | disclosed |
| US-20080070123-A1 | NONAQUEOUS ELECTROLYTE SOLUTION FOR SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | SANYO ELECTRIC CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20060035155-A1 | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery | SANYO ELECTRIC CO., LTD. (JP) | 2006-02-16 | — | — | US | disclosed |