Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.79 |
| ▸ | HCK | P08631 | 14/20 | 0.79 |
| ▸ | FYN | P06241 | 2/20 | 0.66 |
| ▸ | LYN | P07948 | 2/20 | 0.66 |
| ▸ | FGR | P09769 | 2/20 | 0.66 |
| ▸ | SRC | P12931 | 2/20 | 0.66 |
| ▸ | TEK | Q02763 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017604 | 0.94 | LCK (0.89) | LCKHCKFYNLYNFGR | |
| Acetic Acid SCHEMBL5017593 | 0.92 | LCK (0.78) | LCKHCKFYNLYNFGR | |
| SCHEMBL3526861 | 0.88 | LCK (0.82) | LCKHCKFYNLYNFGR | |
| SCHEMBL5025702 | 0.88 | LCK (0.86) | LCKHCKFYNLYNFGR | |
| SCHEMBL3527984 | 0.88 | LCK (0.89) | LCKHCKFYNLYNFGR | |
| SCHEMBL3530173 | 0.87 | LCK (0.89) | LCKHCKFYNLYNFGR | |
| SCHEMBL3528483 | 0.87 | LCK (1.00) | LCKHCKFYNLYNFGR | |
| SCHEMBL5016877 | 0.87 | LCK (0.85) | LCKHCKFYNLYNFGR | |
| SCHEMBL3529696 | 0.87 | LCK (0.81) | LCKHCKFYNLYNFGR | |
| SCHEMBL3530810 | 0.87 | LCK (0.88) | LCKHCKFYNLYNFGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648905-B1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | disclosed |