Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016021 | 0.91 | TRPV1 (0.52) | TRPV1KDM4EGSK3BATG4BAOC3 | |
| SCHEMBL6438919 | 0.88 | TRPV1 (0.50) | TRPV1KDM4EGSK3BATG4BNAMPT | |
| SCHEMBL5063857 | 0.82 | MEN1 (0.56) | TRPV1KDM4EGSK3BATG4B | |
| SCHEMBL4019243 | 0.76 | TRPV1 (0.70) | TRPV1KDM4EGSK3B | |
| SCHEMBL5017508 | 0.76 | CLK4 (0.67) | TRPV1 | |
| SCHEMBL4027136 | 0.74 | TRPV1 (0.58) | TRPV1KDM4EMAPK1 | |
| SCHEMBL5017555 | 0.73 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL1514314 | 0.72 | KDM4E (0.84) | TRPV1KDM4EGSK3BCFDIKBKB | |
| SCHEMBL5016008 | 0.72 | KDM4E (0.51) | TRPV1KDM4EGSK3BATG4B | |
| SCHEMBL2724934 | 0.70 | TRPV1 (0.71) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660455-B1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LAB (US) | 2008-10-15 | — | — | EP | claimed |