Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569455 | 0.85 | SOS1 (0.43) | BTKPIK3CD | |
| SCHEMBL4569452 | 0.84 | BTK (0.45) | BTKPIK3CDPIK3R2 | |
| SCHEMBL16269984 | 0.79 | BTK (0.41) | BTKPIK3CD | |
| SCHEMBL16269983 | 0.78 | BTK (0.45) | BTKPIK3CDPIK3R2 | |
| SCHEMBL16269985 | 0.77 | PIK3CD (0.41) | BTKPIK3CDPIK3R2 | |
| SCHEMBL4569456 | 0.77 | SOS1 (0.43) | BTKPIK3CDPIK3R2 | |
| SCHEMBL4569515 | 0.75 | PIK3CD (0.42) | BTKPIK3CDPIK3R2 | |
| SCHEMBL16269982 | 0.75 | CNR2 (0.46) | BTKPIK3CDPIK3R2 | |
| SCHEMBL4569453 | 0.75 | BTK (0.42) | BTKPIK3CDPIK3R2 | |
| SCHEMBL4569454 | 0.74 | SOS1 (0.39) | BTKPIK3CDPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064973-A2 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |