Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226601 | 1.00 | ESR1 (0.66) | ESR1CYP19A1 | |
| SCHEMBL15226600 | 1.00 | ESR1 (0.66) | ESR1CYP19A1 | |
| SCHEMBL19465651 | 0.88 | ESR1 (0.64) | ESR1 | |
| SCHEMBL19465650 | 0.88 | ESR1 (0.64) | ESR1 | |
| SCHEMBL795926 | 0.88 | ESR1 (0.78) | ESR1 | |
| SCHEMBL795927 | 0.88 | ESR1 (0.78) | ESR1 | |
| SCHEMBL18260700 | 0.87 | ESR1 (0.62) | ESR1CYP19A1 | |
| SCHEMBL18260699 | 0.87 | ESR1 (0.62) | ESR1CYP19A1 | |
| SCHEMBL18260797 | 0.87 | CYP19A1 (0.67) | ESR1CYP19A1 | |
| SCHEMBL18260800 | 0.87 | CYP19A1 (0.67) | ESR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130231333-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-09-05 | — | — | US | claimed |
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20190233897-A1 | NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF | FOUNDATION MEDICINE, INC. | 2019-08-01 | — | — | US | disclosed |
| US-20190233897-A1 | NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF | FOUNDATION MEDICINE, INC. | 2019-08-01 | — | — | US | disclosed |
| US-10093983-B2 | Estrogen receptor mutations and uses thereof | FOUNDATION MEDICINE, INC. (US) | 2018-10-09 | — | — | US | disclosed |
| US-9868704-B2 | Estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-9868704-B2 | Estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-9868704-B2 | Estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160297767-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-10-13 | — | — | US | disclosed |
| US-20160297767-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-10-13 | — | — | US | disclosed |
| US-20160145691-A1 | NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF | FOUNDATION MEDICINE, INC. | 2016-05-26 | — | — | US | disclosed |
| US-20160145691-A1 | NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF | FOUNDATION MEDICINE, INC. | 2016-05-26 | — | — | US | disclosed |
| EP-2735562-B1 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2735562-A1 | Estrogen receptor modulators and uses thereof | Seragon Pharmaceuticals, Inc. (US) | 2014-05-28 | — | — | EP | disclosed |
| EP-2735562-A1 | Estrogen receptor modulators and uses thereof | Seragon Pharmaceuticals, Inc. (US) | 2014-05-28 | — | — | EP | disclosed |
| US-20130231333-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130231333-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130231333-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| WO-2012037411-A9 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012037411-A2 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145691-A1 | NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF | ESR1, ESR2, ESRRG | ESR1 1/4885CYP19A1 8/4885 |
| US-20190233897-A1 | NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF | ESR1, ESR2, ESRRG | ESR1 1/4885CYP19A1 8/4885 |
| US-20130231333-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ESR2, ESRRG, GPER1 | ESR1 4/4885CYP19A1 11/4885 |
| US-10093983-B2 | Estrogen receptor mutations and uses thereof | ESR1, ESR2, ESRRG | ESR1 1/4885CYP19A1 7/4885 |
| US-20160297767-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ESR2, ESRRG, GPER1 | ESR1 4/4885CYP19A1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.