Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020039 | 0.86 | GRM2 (0.75) | GRM2SLC6A3HTR2A | |
| SCHEMBL4561024 | 0.86 | GRM2 (1.00) | GRM2SLC6A3HTR2A | |
| SCHEMBL5020037 | 0.86 | GRM2 (0.57) | GRM2SLC6A3HTR2A | |
| SCHEMBL752397 | 0.85 | GRM2 (0.78) | GRM2SLC6A3HTR2A | |
| SCHEMBL5020051 | 0.84 | GRM2 (0.75) | GRM2SLC6A3HTR2A | |
| SCHEMBL5020024 | 0.80 | GRM2 (0.74) | GRM2SLC6A3HTR2A | |
| SCHEMBL747787 | 0.75 | GRM2 (1.00) | GRM2SLC6A3HTR2A | |
| SCHEMBL750690 | 0.74 | GRM2 (0.79) | GRM2SLC6A3HTR2A | |
| SCHEMBL4562040 | 0.73 | GRM2 (1.00) | GRM2SLC6A3HTR2A | |
| SCHEMBL15226722 | 0.72 | GRM2 (1.00) | GRM2SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062752-A1 | RADIOLABELLED mGLuR2 PET LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2012-05-18 | — | — | WO | disclosed |