Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021869 | 0.83 | GRM5 (0.57) | GRM5PGRKCNH2 | |
| SCHEMBL5021968 | 0.81 | GRM5 (0.73) | GRM5PGRKCNH2 | |
| SCHEMBL5021969 | 0.81 | GRM5 (0.73) | GRM5PGRKCNH2 | |
| SCHEMBL4540474 | 0.80 | GRM5 (0.50) | GRM5PGRKCNH2 | |
| SCHEMBL4537625 | 0.80 | GRM5 (0.71) | GRM5PGRKCNH2 | |
| SCHEMBL16364183 | 0.76 | GRM5 (0.67) | GRM5PGRKCNH2 | |
| SCHEMBL16363933 | 0.76 | GRM5 (0.62) | GRM5PGRKCNH2 | |
| SCHEMBL5021769 | 0.76 | GRM5 (0.55) | GRM5PGRKCNH2 | |
| SCHEMBL13642152 | 0.74 | GRM5 (0.53) | GRM5 | |
| SCHEMBL5021545 | 0.74 | GRM5 (0.53) | GRM5PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |