Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022138 | 0.88 | GRM5 (0.55) | GRM5 | |
| SCHEMBL5022139 | 0.88 | GRM5 (0.55) | GRM5 | |
| SCHEMBL5022091 | 0.86 | GRM5 (0.71) | GRM5 | |
| SCHEMBL13642274 | 0.86 | GRM5 (0.71) | GRM5 | |
| SCHEMBL4561532 | 0.84 | GRM5 (1.00) | GRM5 | |
| SCHEMBL13585577 | 0.84 | GRM5 (1.00) | GRM5 | |
| SCHEMBL4539727 | 0.80 | GRM5 (0.67) | GRM5 | |
| SCHEMBL16363427 | 0.80 | GRM5 (0.60) | GRM5 | |
| SCHEMBL16363933 | 0.80 | GRM5 (0.62) | GRM5 | |
| SCHEMBL5021968 | 0.79 | GRM5 (0.73) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |