Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.79 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021708 | 0.92 | GRM5 (0.79) | GRM5PGRKCNH2 | |
| SCHEMBL5021918 | 0.92 | GRM5 (0.79) | GRM5PGRKCNH2 | |
| SCHEMBL5021715 | 0.90 | GRM5 (0.80) | GRM5PGRKCNH2 | |
| SCHEMBL5021705 | 0.89 | GRM5 (0.82) | GRM5PGRKCNH2 | |
| SCHEMBL5021922 | 0.88 | GRM5 (0.80) | GRM5PGRKCNH2 | |
| SCHEMBL4542789 | 0.88 | GRM5 (1.00) | GRM5PGRKCNH2 | |
| SCHEMBL4542799 | 0.88 | GRM5 (1.00) | GRM5PGRKCNH2 | |
| SCHEMBL30795982 | 0.88 | GRM5 (0.79) | GRM5PGRKCNH2 | |
| SCHEMBL4559581 | 0.88 | GRM5 (0.79) | GRM5PGRKCNH2 | |
| SCHEMBL16324560 | 0.87 | GRM5 (1.00) | GRM5PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |