Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.82 |
| ▸ | PGR | P06401 | 1/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585316 | 1.00 | GRM5 (0.82) | GRM5PGRKCNH2 | |
| SCHEMBL5021955 | 0.93 | GRM5 (0.86) | GRM5PGRKCNH2 | |
| SCHEMBL5021575 | 0.92 | GRM5 (0.81) | GRM5PGRKCNH2 | |
| SCHEMBL4541797 | 0.92 | GRM5 (0.81) | GRM5PGRKCNH2 | |
| SCHEMBL4537080 | 0.92 | GRM5 (0.81) | GRM5PGRKCNH2 | |
| SCHEMBL13585312 | 0.90 | GRM5 (0.85) | GRM5PGRKCNH2 | |
| SCHEMBL4541079 | 0.90 | GRM5 (1.00) | GRM5PGRKCNH2 | |
| SCHEMBL30795482 | 0.90 | GRM5 (1.00) | GRM5PGRKCNH2 | |
| SCHEMBL5022150 | 0.90 | GRM5 (1.00) | GRM5PGRKCNH2 | |
| SCHEMBL13585393 | 0.90 | GRM5 (0.77) | GRM5PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |