Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16363895 | 0.89 | GRM5 (0.46) | GRM5 | |
| SCHEMBL13640450 | 0.86 | GRM5 (0.68) | GRM5 | |
| SCHEMBL4562636 | 0.86 | GRM5 (0.68) | GRM5 | |
| SCHEMBL5021524 | 0.84 | GRM5 (0.48) | GRM5 | |
| SCHEMBL5021518 | 0.84 | GRM5 (0.48) | GRM5 | |
| SCHEMBL5021530 | 0.84 | GRM5 (0.48) | GRM5 | |
| SCHEMBL5021523 | 0.84 | GRM5 (0.48) | GRM5 | |
| SCHEMBL4543613 | 0.81 | GRM5 (0.72) | GRM5 | |
| SCHEMBL4538731 | 0.81 | GRM5 (0.72) | GRM5 | |
| SCHEMBL4537507 | 0.81 | GRM5 (0.72) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |