Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022116 | 1.00 | GRM5 (0.45) | GRM5CYP2D6CA2 | |
| SCHEMBL16364143 | 0.88 | GRM5 (0.47) | GRM5 | |
| SCHEMBL13640359 | 0.85 | GRM5 (0.70) | GRM5 | |
| SCHEMBL13640451 | 0.85 | GRM5 (0.70) | GRM5 | |
| SCHEMBL3988577 | 0.77 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL14508491 | 0.77 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL2798313 | 0.77 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL13067504 | 0.77 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL1443275 | 0.77 | GRM5 (0.66) | GRM5CYP2D6CA2 | |
| SCHEMBL5022056 | 0.75 | GRM5 (0.50) | GRM5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |