SCHEMBL5022336

SCHEMBL5022336

CO/N=C(/C(=O)O)c1ccccc1COc1ccc(C)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.57
PTPRC P08575 1/20 0.46
PTPN1 P18031 1/20 0.46
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
OPRL1 P41146 1/20 0.44
MAOB P27338 1/20 0.43
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624119 1.00 HIF1A (0.57) HIF1APTPRCPTPN1FFAR1FFAR4
SCHEMBL8623308 0.92 HIF1A (0.65) HIF1APTPRCPTPN1ALDH1A1MAOB
SCHEMBL8623305 0.92 HIF1A (0.65) HIF1APTPRCPTPN1ALDH1A1MAOB
SCHEMBL4564428 0.89 HIF1A (0.71) HIF1AFFAR1FFAR4MEN1KMT2A
SCHEMBL8618325 0.89 HIF1A (0.58) HIF1APTPRCPTPN1ALDH1A1HPGD
SCHEMBL8618321 0.89 HIF1A (0.58) HIF1APTPRCPTPN1ALDH1A1HPGD
SCHEMBL8621331 0.86 HIF1A (0.65) HIF1AMEN1KMT2AALDH1A1MAPT
SCHEMBL8621229 0.86 HIF1A (0.59) HIF1AHPGDNPC1RAB9AMAPT
SCHEMBL8621231 0.86 HIF1A (0.59) HIF1AHPGDNPC1RAB9AMAPT
SCHEMBL28895893 0.86 HIF1A (0.63) HIF1APTPRCPTPN1MAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080200334-A1 Method For Enhancing The Effectiveness Of Ethaboxam BASF AKTIENGESELLSCHAFT (DE) 2008-08-21 US disclosed
EP-0951831-B1 Fungicidal co-formulation BASF AG (DE) 2003-06-11 EP disclosed
EP-0951831-A1 Fungicidal co-formulation American Cyanamid Company (US) 1999-10-27 EP disclosed
EP-0658541-B1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE SHIONOGI & CO (JP) 1998-05-20 EP disclosed
US-5510506-A Process for producing carboxylic acid derivatives SHIONOGI & CO., LTD. (JP) 1996-04-23 US disclosed
EP-0658541-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE SHIONOGI & CO., LTD. (JP) 1995-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200334-A1 Method For Enhancing The Effectiveness Of Ethaboxam MANBA, MAN2A1, CMA1 HIF1A 4679/4885PTPRC 2859/4885PTPN1 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.