Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL502248 | 1.00 | — | — | |
| Methacrylic Acid SCHEMBL268854 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL727325 | 0.96 | TDP1 (0.50) | — | |
| Methacrylic Acid SCHEMBL727324 | 0.96 | TDP1 (0.50) | — | |
| Methacrylic Acid SCHEMBL2991 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL10900651 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL28518987 | 0.96 | TDP1 (0.50) | — | |
| Methacrylic Acid SCHEMBL14721919 | 0.92 | — | — | |
| Methacrylic Acid SCHEMBL7887489 | 0.92 | — | — | |
| Methacrylic Acid SCHEMBL31409470 | 0.92 | TDP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095177-A1 | FLUORINATED POLY(ETHER)S END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | SANTARUS, INC. | 2012-04-19 | — | — | US | disclosed |
| US-8105623-B2 | Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2012-01-31 | — | — | US | disclosed |
| EP-2035480-B1 | FLUORINATED POLY (ETHER)S END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | BAUSCH & LOMB (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-2035480-A1 | FLUORINATED POLY (ETHER)S END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | Bausch & Lomb Incorporated (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008005652-A1 | FLUORINATED POLY (ETHER)S END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20080003261-A1 | Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups | Salix Pharmaceuticals, Ltd | 2008-01-03 | — | — | US | disclosed |
| US-5839037-A | Method for transferring a liquid image | XEROX CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| EP-0747786-A2 | A method of transferring a liquid image | XEROX CORPORATION (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5476743-A | Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant | XEROX CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0684525-A1 | Liquid developer compositions with block copolymers | XEROX CORPORATION (US) | 1995-11-29 | — | — | EP | disclosed |