Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712075 | 0.90 | DPP4 (0.64) | DPP4ARDPP8DPP9GPR119 | |
| SCHEMBL2711530 | 0.84 | DPP4 (0.56) | DPP4DPP8DPP9IRAK4 | |
| SCHEMBL2711283 | 0.79 | DPP4 (0.49) | DPP4ABL1BCR | |
| SCHEMBL2707234 | 0.77 | DPP4 (0.60) | DPP4DPP8DPP9GPR119 | |
| SCHEMBL2710752 | 0.77 | DPP4 (0.47) | DPP4DPP8DPP9 | |
| SCHEMBL2708924 | 0.77 | DPP4 (0.64) | DPP4ARDPP8DPP9GPR119 | |
| SCHEMBL2710061 | 0.75 | DPP4 (0.58) | DPP4ARDPP8DPP9 | |
| SCHEMBL2710588 | 0.75 | DPP4 (0.48) | DPP4 | |
| SCHEMBL2710450 | 0.75 | NPC1 (0.49) | DPP4 | |
| SCHEMBL2711745 | 0.74 | DPP4 (0.50) | DPP4ARDPP8DPP9IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |