SCHEMBL5023554

SCHEMBL5023554

CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)ON1C(=O)CCC1=O)C(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
SIRT2 Q8IXJ6 4/20 0.44
SIRT1 Q96EB6 2/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
SIRT3 Q9NTG7 1/20 0.44
FAAH O00519 2/20 0.43
PSMB5 P28074 1/20 0.43
LPAR1 Q92633 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28975556 1.00 KMT2A (0.52) KMT2AMEN1ALDH1A1HPGDSIRT2
SCHEMBL28975537 1.00 KMT2A (0.52) KMT2AMEN1ALDH1A1HPGDSIRT2
SCHEMBL23497284 0.93 KMT2A (0.56) KMT2AMEN1ALDH1A1HPGDSIRT2
SCHEMBL23497285 0.93 KMT2A (0.56) KMT2AMEN1ALDH1A1HPGDSIRT2
SCHEMBL12275328 0.92 KMT2A (0.46) KMT2AMEN1ALDH1A1HPGDFAAH
SCHEMBL15723491 0.92 KMT2A (0.46) KMT2AMEN1ALDH1A1HPGDFAAH
SCHEMBL2151046 0.92 KMT2A (0.46) KMT2AMEN1ALDH1A1HPGDFAAH
SCHEMBL15450633 0.87 ACE (0.45) KMT2AMEN1ALDH1A1HPGDBCHE
SCHEMBL7130286 0.87 BCHE (0.48) KMT2AMEN1ALDH1A1HPGDSIRT2
SCHEMBL2151047 0.86 KMT2A (0.48) KMT2AMEN1ALDH1A1HPGDFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872915-A Liraglutide side chain single crystal and culture method thereof 宜昌东阳光长江药业股份有限公司 2023-03-31 CN disclosed
EP-1956000-B1 ACYLATING AGENTS USEFUL FOR ACYLATING PEPTIDES NOVO NORDISK AS (DK) 2016-10-05 EP disclosed
EP-1163211-B1 METHOD FOR ACYLATING PEPTIDES AND PROTEINS NOVO NORDISK AS (DK) 2008-09-24 EP disclosed
EP-1956000-A1 Acylating agents useful for acylating peptides Novo Nordisk A/S (DK) 2008-08-13 EP disclosed
US-6451974-B1 GLUTAMIC ACID DERIVATIVE; SAPONIFICATION; RACEMIZATION PREVENTION NOVO NORDISK A/S (DK) 2002-09-17 US disclosed
EP-1163211-A1 METHOD FOR ACYLATING PEPTIDES AND NOVEL ACYLATING AGENTS NOVO NORDISK A/S (DK) 2001-12-19 EP disclosed
WO-2000055119-A1 METHOD FOR ACYLATING PEPTIDES AND NOVEL ACYLATING AGENTS NOVO NORDISK A/S (DK) 2000-09-21 WO disclosed