Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299220 | 0.89 | MEN1 (0.55) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5024417 | 0.87 | MEN1 (0.53) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019032 | 0.84 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL13365288 | 0.84 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019122 | 0.84 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL2748789 | 0.84 | MAPT (0.51) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019066 | 0.82 | PSMB5 (0.51) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019079 | 0.82 | PSMB5 (0.51) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL2748425 | 0.81 | PSMB5 (0.49) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL13290795 | 0.81 | PSMB5 (0.55) | MEN1KMT2AALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |