Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.85 |
| ▸ | FYN | P06241 | 5/20 | 0.85 |
| ▸ | KDR | P35968 | 2/20 | 0.85 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.85 |
| ▸ | AURKA | O14965 | 1/20 | 0.85 |
| ▸ | JAK2 | O60674 | 1/20 | 0.85 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.85 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.85 |
| ▸ | PAK4 | O96013 | 1/20 | 0.85 |
| ▸ | ABL1 | P00519 | 1/20 | 0.85 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.85 |
| ▸ | CSF1R | P07333 | 1/20 | 0.85 |
| ▸ | RET | P07949 | 1/20 | 0.85 |
| ▸ | MET | P08581 | 1/20 | 0.85 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.85 |
| ▸ | PIM1 | P11309 | 1/20 | 0.85 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.85 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.85 |
| ▸ | PRKACA | P17612 | 1/20 | 0.85 |
| ▸ | FLT1 | P17948 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024062 | 1.00 | LCK (0.85) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5025732 | 0.96 | LCK (0.87) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5025737 | 0.96 | LCK (0.87) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5025636 | 0.94 | LCK (0.84) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5025628 | 0.94 | LCK (0.84) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5015599 | 0.94 | LCK (0.83) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5015607 | 0.94 | LCK (0.83) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5024046 | 0.93 | LCK (0.84) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5024035 | 0.93 | LCK (0.84) | LCKFYNKDRCHEK1AURKA | |
| SCHEMBL5015562 | 0.93 | LCK (0.87) | LCKFYNKDRCHEK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648905-B1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | disclosed |