Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TYMS | P04818 | 2/20 | 0.53 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180945 | 1.00 | POLB (0.55) | POLBTYMSTK1 | |
| SCHEMBL9900767 | 1.00 | POLB (0.55) | POLBTYMSTK1 | |
| SCHEMBL13899894 | 0.94 | POLB (0.53) | POLBTYMS | |
| SCHEMBL13224513 | 0.94 | POLB (0.53) | POLBTYMS | |
| SCHEMBL19681270 | 0.93 | POLB (0.52) | POLBTYMS | |
| SCHEMBL16416278 | 0.93 | POLB (0.52) | POLBTYMS | |
| SCHEMBL14661236 | 0.92 | POLB (0.56) | POLB | |
| SCHEMBL14661232 | 0.92 | POLB (0.56) | POLB | |
| SCHEMBL16038405 | 0.92 | POLB (0.51) | POLBTYMS | |
| SCHEMBL224861 | 0.90 | POLG (0.55) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220145303-A1 | FRAGILE X MENTAL RETARDATION PROTEIN INTERFERING OLIGONUCLEOTIDES AND METHODS OF USING SAME | NOGRA PHARMA LTD (IE) | 2022-05-12 | — | — | US | claimed |
| US-20200325480-A1 | Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field | NOGRA PHARMA LTD (IE) | 2020-10-15 | — | — | US | claimed |
| US-10738309-B2 | Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field | NOGRA PHARMA LIMITED (IE) | 2020-08-11 | — | — | US | claimed |
| US-20200181622-A1 | Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field | GIULIANI INTERNATIONAL, LTD. (IE) | 2020-06-11 | — | — | US | claimed |
| US-10633660-B2 | Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field | NOGRA PHARMA LIMITED (IE) | 2020-04-28 | — | — | US | claimed |
| US-20190211336-A1 | Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field | GIULIANI INTERNATIONAL, LTD. (IE) | 2019-07-11 | — | — | US | claimed |
| US-10036022-B2 | Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field | NOGRA PHARMA LIMITED (IE) | 2018-07-31 | — | — | US | claimed |
| US-9951334-B2 | Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field | NOGRA PHARMA LIMITED (IE) | 2018-04-24 | — | — | US | claimed |
| US-20180030450-A1 | Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field | GIULIANI INTERNATIONAL, LTD. (IE) | 2018-02-01 | — | — | US | claimed |
| US-20170253880-A1 | Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field | GIULIANI INTERNATIONAL, LTD. (IE) | 2017-09-07 | — | — | US | claimed |
| US-8106182-B2 | Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field | GIULIANI INTERNATIONAL LIMITED (IE) | 2012-01-31 | — | — | US | claimed |
| JP-4559411-B2 | — | — | 2010-10-06 | — | — | JP | claimed |
| US-7700757-B2 | for treatment of chronic inflammatory bowel disease, Crohn's disease and ulcerative colitis | GIULIANI INTERNAITONAL LIMITED (IE) | 2010-04-20 | — | — | US | claimed |
| EP-1608753-B1 | ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES IN MEDICAL FIELD THEREOF | GIULIANI INT LTD (IE) | 2008-12-10 | — | — | EP | claimed |
| US-20070167385-A1 | for treatment of chronic inflammatory bowel disease, Crohn's disease and ulcerative colitis | NOGRA PHARMA LIMITED (IE) | 2007-07-19 | — | — | US | claimed |
| US-20070042985-A1 | Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field | GIULIANI INTERNATIONAL LIMITED (IE) | 2007-02-22 | — | — | US | claimed |
| JP-2006521815-A | — | — | 2006-09-28 | — | — | JP | claimed |
| EP-1608753-A1 | ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES IN MEDICAL FIELD THEREOF | Giuliani International Limited (IE) | 2005-12-28 | — | — | EP | claimed |
| WO-2004087920-A1 | ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES IN MEDICAL FIELD THEREOF | GIULIANI INTERNATIONAL LIMITED (IE) | 2004-10-14 | — | — | WO | claimed |
| CN-1434723-A | Immunostimulatory oligodeoxynucleotides | CISTEM BIOTECHNOLOGIES GMBH (AT) | 2003-08-06 | — | — | CN | claimed |