Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thiophene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29616843 | 1.00 | LCK (0.47) | — | |
| Thiophene SCHEMBL28167483 | 1.00 | LCK (0.47) | — | |
| Thiophene SCHEMBL28550995 | 1.00 | LCK (0.47) | — | |
| Acetic Acid SCHEMBL755556 | 1.00 | LCK (0.47) | — | |
| Thiophene SCHEMBL936675 | 0.97 | FFAR3 (0.44) | — | |
| Thiophene SCHEMBL28856570 | 0.97 | FFAR3 (0.44) | — | |
| Thiophene SCHEMBL28163543 | 0.97 | FFAR3 (0.44) | — | |
| Thiophene SCHEMBL27698822 | 0.97 | FFAR3 (0.44) | — | |
| Thiophene SCHEMBL27849176 | 0.97 | FFAR3 (0.44) | — | |
| Thiophene SCHEMBL27618627 | 0.97 | FFAR3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250072423-A1 | THIOPHENE ACETIC ACID FOR PLANT GROWTH REGULATION | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2025-03-06 | — | — | US | claimed |
| US-12183926-B2 | Lithium secondary battery polymer material and manufacturing method therefor | LG ENERGY SOLUTION, LTD. (KR) | 2024-12-31 | — | — | US | claimed |
| US-12029216-B1 | Thiophene acetic acid for plant growth regulation | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2024-07-09 | — | — | US | claimed |
| CN-118271624-A | Amphiphilic block copolymer and preparation method and application thereof | 广州孔确基因科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-117643367-A | Blended spicy and hot grilled fish essence and preparation method thereof | 宁夏春升源生物科技有限公司 | 2024-03-05 | — | — | CN | claimed |
| EP-3664199-B1 | LITHIUM SECONDARY BATTERY POLYMER MATERIAL AND MANUFACTURING METHOD THEREFOR | LG ENERGY SOLUTION LTD (KR) | 2023-08-30 | — | — | EP | claimed |
| US-11697104-B2 | Method for preparing, in situ, metal-organic framework by using control of diffusion within ionic polymer | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-07-11 | — | — | US | claimed |
| CN-111033835-B | Lithium secondary battery polymer material and method for producing same | 株式会社LG新能源 | 2023-05-09 | — | — | CN | claimed |
| CN-114605375-B | Synthetic method of 2-thiopheneacetic acid | 沈阳化工研究院有限公司 | 2023-04-11 | — | — | CN | claimed |
| US-20220346679-A1 | ANALYTE MEASUREMENT SYSTEM | WearOptimo Pty Ltd (AU) | 2022-11-03 | — | — | US | claimed |
| CN-102892765-A | Novel cyclohexylamine derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonist activity | ALMIRALL SA | 2013-01-23 | — | — | CN | claimed |
| CN-102343210-B | Method for comprehensively recycling SO2 in waste ammonia gas and flue gas generated by thiophene acetic acid | LINHAI LIMIN CHEMICALS CO LTD | 2012-12-19 | — | — | CN | claimed |
| US-8114832-B2 | Conformational altered protein; contacting with drug capable of binding; forming fusion protein; detection; side effect reduction | CROSSBETA BIOSCIENCES B.V. (NL) | 2012-02-14 | — | — | US | claimed |
| CN-102343210-A | Method for comprehensively recycling SO2 in waste ammonia gas and flue gas generated by thiophene acetic acid | LINHAI LIMIN CHEMICALS CO LTD | 2012-02-08 | — | — | CN | claimed |
| WO-2009134227-A1 | POL YARYLENE POLYMERS RESULTING FROM DIELS-ALDER REACTION | ENERGY MATERIALS CORPORATION (US) | 2009-11-05 | — | — | WO | claimed |
| US-20090264544-A1 | Polyarylene polymers and ion conducting functionalized polyarylene polymers resulting from pairing bis-diene arylenes and bis-dienophile arylenes via a diels-alder reaction | ENERGY MATERIALS CORPORATION | 2009-10-22 | — | — | US | claimed |
| CN-1644678-A | Bacteria for degradating thiosulfur efficiently | UNIV SHANDONG (CN) | 2005-07-27 | — | — | CN | claimed |
| CN-1435692-A | Fluorescent analysis reagent for testing blood homo cysteine, method for preparing same and use thereof | LI QIN (CN) | 2003-08-13 | — | — | CN | claimed |
| CN-1030239-C | Arthropodicidal composition comprising thiodicarb and phenylpyrazole | RHONE POULENC AGRICULTURE (GB) | 1995-11-15 | — | — | CN | claimed |
| US-4719224-A | ANALGESICS, ANTIINFLAMMATORY | ROUSSEL UCLAF (FR) | 1988-01-12 | — | — | US | claimed |