Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 18/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024443 | 1.00 | LSS (0.52) | LSSKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL4804179 | 0.88 | LSS (0.52) | LSS | |
| SCHEMBL4804176 | 0.88 | LSS (0.52) | LSS | |
| SCHEMBL4802764 | 0.88 | LSS (0.57) | LSS | |
| SCHEMBL4806283 | 0.85 | LSS (0.50) | LSS | |
| SCHEMBL4806289 | 0.85 | LSS (0.50) | LSS | |
| SCHEMBL4802753 | 0.81 | LSS (0.50) | LSS | |
| SCHEMBL4802760 | 0.81 | LSS (0.50) | LSS | |
| SCHEMBL4803046 | 0.80 | LSS (0.52) | LSS | |
| SCHEMBL4803040 | 0.80 | LSS (0.52) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-B1 | AMINOCYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |