Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300675 | 0.77 | CPT2 (0.38) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL26984814 | 0.76 | HMGCR (0.39) | SLC22A6ALDH1A1TDP1FFAR3PGD | |
| SCHEMBL31430102 | 0.73 | SLC22A6 (0.31) | SLC22A6MEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL14261124 | 0.73 | SLC22A6 (0.38) | SLC22A6TDP1FFAR3PGDGPR84 | |
| SCHEMBL15555383 | 0.73 | SLC22A6 (0.38) | SLC22A6TDP1FFAR3PGDGPR84 | |
| SCHEMBL1201912 | 0.72 | SLC22A6 (0.30) | SLC22A6 | |
| SCHEMBL16467958 | 0.71 | TSHR (0.40) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL20702119 | 0.71 | CPT2 (0.35) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL1604218 | 0.71 | SLC22A6 (0.36) | SLC22A6TDP1FFAR3GPR84 | |
| SCHEMBL17467172 | 0.71 | TDP1 (0.36) | CPT2SLC22A6TDP1FFAR3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772646-B1 | FLUOROELASTOMER MOULDING PROCESS | DU PONT (US) | 2000-03-01 | — | — | EP | claimed |
| EP-0772646-A4 | FLUOROELASTOMER MOULDING PROCESS | DU PONT (US) | 1997-12-10 | — | — | EP | claimed |
| EP-0772646-A1 | FLUOROELASTOMER MOULDING PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1996001870-A1 | FLUOROELASTOMER MOULDING PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-25 | — | — | WO | claimed |
| EP-0691371-A1 | Fluoroelastomer compositions | DU PONT DE NEMOURS INTERNATIONAL S.A. (CH) | 1996-01-10 | — | — | EP | claimed |
| WO-2013143881-A1 | CARBOXYLIC ESTER OR POLYETHER ESTER AS PROCESSING AID FOR FLUORO RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| EP-2644648-A1 | Carboxylic acid esters or polyetheresters as a processing aid for fluoro-rubbers | LANXESS Deutschland GmbH (DE) | 2013-10-02 | — | — | EP | disclosed |
| US-7420078-B2 | Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3,5-dihydroxy heptanoic acid derivatives, and intermediates thereof | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-09-02 | — | — | US | disclosed |
| US-7317123-B2 | Process for preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation | TEVA PHARMACEUTICAL INDUSTRIES, LTD (IL) | 2008-01-08 | — | — | US | disclosed |
| US-20040242916-A1 | Process for preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation | BASF SE (DE) | 2004-12-02 | — | — | US | disclosed |
| US-20040186313-A1 | Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3 5-dihydroxy heptanoic acid derivatives, and intermediates thereof | CIBA SPECIALTY CHEMICALS CORP. | 2004-09-23 | — | — | US | disclosed |
| EP-0772646-B1 | FLUOROELASTOMER MOULDING PROCESS | DU PONT (US) | 2000-03-01 | — | — | EP | disclosed |
| EP-0772646-A4 | FLUOROELASTOMER MOULDING PROCESS | DU PONT (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0772646-A1 | FLUOROELASTOMER MOULDING PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996001870-A1 | FLUOROELASTOMER MOULDING PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-25 | — | — | WO | disclosed |
| EP-0691371-A1 | Fluoroelastomer compositions | DU PONT DE NEMOURS INTERNATIONAL S.A. (CH) | 1996-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186313-A1 | Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3 5-dihydroxy heptanoic acid derivatives, and intermediates thereof | HMGCR, CYP46A1, CYP7A1 | CPT2 586/4885ACLY 1251/4885HSPD1 3928/4885 |
| US-20040242916-A1 | Process for preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation | HMGCR, DHCR7, CYP8B1 | CPT2 1710/4885ACLY 1672/4885HSPD1 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.