Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023520 | 0.93 | EGFR (0.65) | EGFR | |
| SCHEMBL5400957 | 0.92 | EGFR (0.60) | EGFR | |
| Hydrochloric Acid SCHEMBL5023596 | 0.92 | EGFR (0.65) | EGFR | |
| SCHEMBL4445113 | 0.84 | EGFR (0.75) | EGFR | |
| SCHEMBL5023579 | 0.84 | EGFR (0.73) | EGFR | |
| Hydrochloric Acid SCHEMBL4448497 | 0.84 | EGFR (0.74) | EGFR | |
| SCHEMBL5022859 | 0.83 | EGFR (0.74) | EGFR | |
| SCHEMBL6010021 | 0.83 | EGFR (0.64) | EGFR | |
| SCHEMBL6009629 | 0.82 | EGFR (0.65) | EGFR | |
| Hydrochloric Acid SCHEMBL5025496 | 0.80 | EGFR (0.65) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1713781-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |