Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028826 | 0.92 | TACR1 (0.47) | TACR1 | |
| SCHEMBL3477895 | 0.84 | TACR1 (0.60) | TACR1 | |
| SCHEMBL7182090 | 0.83 | TACR1 (0.65) | TACR1 | |
| SCHEMBL7180360 | 0.79 | TACR1 (0.65) | TACR1 | |
| SCHEMBL7180363 | 0.79 | TACR1 (0.65) | TACR1 | |
| SCHEMBL7178193 | 0.78 | TACR1 (0.44) | TACR1 | |
| SCHEMBL7178198 | 0.78 | TACR1 (0.44) | TACR1 | |
| SCHEMBL8325709 | 0.77 | TACR1 (0.51) | TACR1 | |
| SCHEMBL8325707 | 0.77 | TACR1 (0.51) | TACR1 | |
| SCHEMBL7181548 | 0.76 | TACR1 (0.53) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898905-A2 | HYDROISOINDOLINE TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007002457-A2 | HYDROISOINDOLINE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |