Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.77 |
| ▸ | LMNA | P02545 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | TSHR | P16473 | 5/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.77 |
| ▸ | PGR | P06401 | 4/20 | 0.77 |
| ▸ | AR | P10275 | 4/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.77 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | SHBG | P04278 | 4/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.67 |
| ▸ | SNCA | P37840 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596443 | 1.00 | CYP3A4 (0.77) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL24102454 | 1.00 | CYP3A4 (0.77) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL5026185 | 1.00 | CYP3A4 (0.77) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL24102479 | 1.00 | CYP3A4 (0.77) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL8814296 | 0.98 | CYP3A4 (0.80) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL6442894 | 0.91 | CYP3A4 (0.80) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL24102393 | 0.90 | CYP3A4 (0.86) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL24102394 | 0.90 | CYP3A4 (0.86) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL9664215 | 0.90 | CYP3A4 (0.79) | CYP3A4LMNAMAPTTSHRNR3C1 | |
| SCHEMBL4617560 | 0.90 | CYP3A4 (0.79) | CYP3A4LMNAMAPTTSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957121-A2 | ACUTE TREATMENT OF SOCIAL PHOBIA | Pherin Pharmaceuticals, Inc. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007030800-A2 | ACUTE TREATMENT OF SOCIAL PHOBIA | PHERIN PHARMACEUTICALS, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
| EP-0296160-A1 | COMBINATION OF AROMATASE INHIBITORS AND 5$g(a)-REDUCTASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-12-28 | — | — | EP | disclosed |
| WO-1987005216-A1 | COMBINATION OF AROMATASE INHIBITORS AND 5alpha-REDUCTASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1987-09-11 | — | — | WO | disclosed |