⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502743 | 0.79 | — | — | |
| SCHEMBL29751880 | 0.79 | — | — | |
| SCHEMBL502594 | 0.79 | — | — | |
| SCHEMBL31345073 | 0.79 | — | — | |
| SCHEMBL25326384 | 0.77 | HTT (0.31) | — | |
| SCHEMBL26023718 | 0.77 | CYP11B1 (0.42) | — | |
| SCHEMBL315335 | 0.75 | — | — | |
| SCHEMBL440236 | 0.75 | — | — | |
| SCHEMBL21408628 | 0.75 | — | — | |
| SCHEMBL13772368 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583866-B2 | Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists | BEONE MEDICINES I GMBH (CH) | 2026-03-24 | — | — | US | disclosed |
| EP-4615578-A1 | CYCLIC PYRIDINE DERIVATIVES AS CGAS INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2025067290-A1 | PYRIMIDOPYRAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 广东东阳光药业股份有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-119707982-A | Pyrimidopyrazoles, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-118772109-A | Pyrazole compound, pharmaceutical composition and application thereof | 中国药科大学 | 2024-10-15 | — | — | CN | disclosed |
| US-12043625-B2 | Pyridine derivatives with c-linked cyclic substituents as cGAS inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12043625-B2 | Pyridine derivatives with c-linked cyclic substituents as cGAS inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12043625-B2 | Pyridine derivatives with c-linked cyclic substituents as cGAS inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20240189315-A1 | Cyclic Pyridine Derivatives as cGAS Inhibitors | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2024-06-13 | — | — | US | disclosed |
| WO-2024099908-A1 | CYCLIC PYRIDINE DERIVATIVES AS CGAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |
| EP-2231663-A2 | FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE AS C-MET INHIBITORS | Amgen, Inc (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20100093807-A1 | SUBSTITUTED 7-AZABICYCLO[2.2.1]HEPTYL DERIVATIVES USEFUL FOR MAKING PHARMACEUTICAL COMPOSITIONS | UNIVERSITEIT GENT (BE) | 2010-04-15 | — | — | US | disclosed |
| US-20090318436-A1 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2009-12-24 | — | — | US | disclosed |
| US-20090318436-A1 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2009-12-24 | — | — | US | disclosed |
| US-20090275616-A1 | STRAIGHTFORWARD ENTRY TO 7-AZABICYCLO[2.2.1]HEPTANE-1-CARBONITRILES AND SUBSEQUENT SYNTHESIS OF EPIBATIDINE ANALOGUES | UNIVERSITEIT GENT (BE) | 2009-11-05 | — | — | US | disclosed |
| WO-2009091374-A2 | FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| US-20090124609-A1 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090124609-A1 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-4822887-A | Preparation of difluoropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0146924-A2 | Preparation of difluorpyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |