SCHEMBL502659

SCHEMBL502659

ClCc1ccc(Br)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29612153 0.98 CYP11B1 (0.44)
Hydrochloric Acid SCHEMBL3073247 0.98 CYP11B1 (0.44)
SCHEMBL10484015 0.80 CYP11B1 (0.42)
SCHEMBL10483902 0.79 CYP11B1 (0.41)
SCHEMBL485115 0.78
SCHEMBL29725206 0.78
SCHEMBL1274691 0.76
SCHEMBL2180629 0.76
SCHEMBL1193384 0.76
SCHEMBL9029193 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166171-B Heterocyclic compound and organic light-emitting device comprising the same LT素材株式会社 2024-05-14 CN disclosed
EP-3559000-B1 BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEIROF BETTA PHARMACEUTICALS CO LTD (CN) 2022-03-23 EP disclosed
CN-105593211-B Indole and indazole derivatives 豪夫迈·罗氏有限公司 2021-07-27 CN disclosed
US-11053238-B2 Benzimidazole derivatives, preparation methods and uses thereof BETTA PHARMACEUTICALS CO., LTD. (CN) 2021-07-06 US disclosed
US-20210130345-A1 BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEREOF BETTA PHARMACEUTICALS CO., LTD. (CN) 2021-05-06 US disclosed
CN-110234652-B Benzimidazole derivative and preparation method and application thereof 贝达药业股份有限公司 2020-11-10 CN disclosed
CN-110234652-A Benzimidazole derivative and preparation method and application thereof 贝达药业股份有限公司 2019-09-13 CN disclosed
WO-2019035008-A1 CDK4/6 INHIBITORS AND USE THEREOF BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2019-02-21 WO disclosed
CN-105153119-B Pyridine pyrimidinamine compound or pyridine pyridyl amine compound and its application 广州必贝特医药技术有限公司 2019-01-01 CN disclosed
EP-3049391-B1 INDOLE AND INDAZOLE DERIVATIVES HOFFMANN LA ROCHE (CH) 2018-12-26 EP disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4812571-A NITROMETHYLENE COMPOUNDS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-03-14 US disclosed
US-4803277-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-02-07 US disclosed
US-4774247-A Nitromethylene derivative insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-09-27 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0259738-A2 Heterocyclic compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-03-16 EP disclosed
EP-0235725-A2 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1987-09-09 EP disclosed
US-4678795-A 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-07-07 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
EP-0163855-A1 Nitromethylene derivatives, intermediates, and process for their preparation as insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-12-11 EP disclosed