SCHEMBL502679

SCHEMBL502679

[CH2]C(O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6777789 1.00
SCHEMBL6428869 1.00
SCHEMBL7708613 0.75
SCHEMBL1509776 0.72
SCHEMBL794633 0.72
SCHEMBL11507765 0.72
SCHEMBL143378 0.70
SCHEMBL5176960 0.70
SCHEMBL1509800 0.70
SCHEMBL1509705 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1052 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4369081-A2 METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT Alcon Inc. (CH) 2024-05-15 EP claimed
US-11975499-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-05-07 US claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
CN-114502362-B Contact lenses with surfaces of different softness 爱尔康公司 2024-03-26 CN claimed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN claimed
CN-114981072-B Wettable silicone hydrogel contact lenses 爱尔康公司 2024-03-26 CN claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-4963543-A BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-10-16 US claimed
EP-0190606-B1 SORBENT FOR THE PURIFICATION OF PROTEINS F. HOFFMANN-LA ROCHE AG (CH) 1990-05-09 EP claimed
US-4716219-A Adsorbent for protein purification HOFFMANN-LA ROCHE INC. (US) 1987-12-29 US claimed
EP-0048614-B1 1-N-ACYLATED AND 1-N-ALKYLATED DERIVATIVES OF 4-0-SUBSTITUTED -2-DEOXYSTREPTAMINE AMINOGLYCOSIDES ELI LILLY AND COMPANY (US) 1985-03-20 EP claimed
EP-0048613-B1 4-0-SUBSTITUTED -2-DEOXYSTREPTAMINE AMINOGLYCOSIDE DERIVATIVES, THEIR PREPARATION AND FORMULATIONS CONTAINING THEM ELI LILLY AND COMPANY (US) 1985-01-23 EP claimed
US-4468512-A 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides ELI LILLY AND COMPANY (US) 1984-08-28 US claimed
US-4468513-A 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides ELI LILLY AND COMPANY (US) 1984-08-28 US claimed
US-4360665-A 4\"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor ELI LILLY AND COMPANY (US) 1982-11-23 US claimed
EP-0048613-A1 4-0-Substituted -2-deoxystreptamine aminoglycoside derivatives, their preparation and formulations containing them ELI LILLY AND COMPANY (US) 1982-03-31 EP claimed
US-4260760-A BACTERICIDES, ALGICIDES MERCK & CO., INC. (US) 1981-04-07 US claimed