Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605851 | 0.88 | CHRM2 (0.43) | KMT2AMEN1RAD52HTTDNMT1 | |
| SCHEMBL5028685 | 0.82 | KMT2A (0.46) | KMT2AMEN1RAD52HTTDNMT1 | |
| SCHEMBL5025352 | 0.82 | BAX (0.56) | KMT2AMEN1RAD52HTTDNM1 | |
| SCHEMBL5022633 | 0.82 | BAX (0.56) | KMT2AMEN1RAD52HTTDNM1 | |
| SCHEMBL5022677 | 0.81 | MEN1 (0.62) | KMT2AMEN1RAD52HTTDNM1 | |
| SCHEMBL5025287 | 0.81 | MEN1 (0.62) | KMT2AMEN1RAD52HTTDNM1 | |
| SCHEMBL5025317 | 0.81 | MEN1 (0.62) | KMT2AMEN1RAD52HTTDNM1 | |
| SCHEMBL5022555 | 0.81 | BAX (0.43) | KMT2AMEN1RAD52HTTDNMT1 | |
| SCHEMBL7649594 | 0.79 | KMT2A (0.44) | KMT2AMEN1RAD52HTTDNMT1 | |
| SCHEMBL607992 | 0.77 | BAX (0.60) | KMT2AMEN1RAD52HTTDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | claimed |