Methacrylic Acid

Methacrylic Acid

SCHEMBL5028039

C=C(C)C(=O)O.C=CC(=O)OCCCCCCOC(=O)C=C

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.73
ALDH1A1 P00352 5/20 0.73
CYP3A4 P08684 2/20 0.73
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
HCAR2 Q8TDS4 3/20 0.44
THRB P10828 2/20 0.42
HTT P42858 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NAAA Q02083 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL11039069 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL14661239 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL11036589 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL11037032 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL20875120 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL25389673 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL3798546 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL5188133 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL20875124 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL6541997 0.93 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348121-B2 Toner, method for manufacturing the toner, developer including the toner, toner container containing the toner, and image forming method, image forming apparatus and process cartridge using the toner RICOH COMPANY LIMITED (JP) 2008-03-25 US disclosed
US-7348117-B2 Toner, method for manufacturing the toner, developer including the toner, toner container containing the toner, and image forming method, image forming apparatus and process cartridge using the toner RICOH COMPANY LIMITED (JP) 2008-03-25 US disclosed
US-20070141506-A1 TONER, METHOD FOR MANUFACTURING THE TONER, DEVELOPER INCLUDING THE TONER, TONER CONTAINER CONTAINING THE TONER, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE TONER INOUE RYOHTA 2007-06-21 US disclosed
US-20050031980-A1 Toner, method for manufacturing the toner, developer including the toner, toner container containing the toner, and image forming method, image forming apparatus and process cartridge using the toner RICOH COMPANY LIMITED (JP) 2005-02-10 US disclosed