SCHEMBL5028587

SCHEMBL5028587

c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
CYP3A4 P08684 1/20 1.00
ESR1 P03372 4/20 0.67
ESR2 Q92731 4/20 0.67
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 3/20 0.40
NPSR1 Q6W5P4 1/20 0.38
DRD1 P21728 2/20 0.37
TSHR P16473 4/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
ALOX12 P18054 2/20 0.35
CA12 O43570 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101 1.00 TDP1 (1.00) TDP1CYP3A4ESR1ESR2KDM4E
Benzene SCHEMBL6890099 1.00 TDP1 (1.00) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL2085135 1.00 TDP1 (1.00) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL1195618 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL22558063 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL25384985 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL22445084 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL20582981 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL521959 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL11170638 0.96 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417618-A The synthetic method of benzophenanthrene benzoyloxy alkynes biphenyl alkynes benzene bridging list imines dihexyl 桂林理工大学 2017-12-01 CN claimed
CN-107082762-A The synthetic method of benzophenanthrene benzoyloxy alkynes benzyne benzene Qiao Lian perylene list imines dihexyls 桂林理工大学 2017-08-22 CN claimed
CN-107043352-A The synthetic method of benzophenanthrene benzoyloxy alkynes benzene Qiao Lian perylene list imines dihexyls 桂林理工大学 2017-08-15 CN claimed
CN-105504186-A Preparing method and application of 3,4-bi(4-cyanophenyl)-2,5-diphenyl phenyl grafted polysiloxane UNIV SHANDONG 2016-04-20 CN claimed
WO-2024005039-A1 METHOD FOR PRODUCING VERY-LONG-CHAIN POLYUNSATURATED FATTY ACID 株式会社ニッスイ 2024-01-04 WO disclosed
WO-2023157772-A1 PROTECTIVE FILM FORMING COMPOSITION 日産化学株式会社 2023-08-24 WO disclosed
WO-2021161360-A1 EPOXY RESIN COMPOSITION, EPOXY RESIN CURED PRODUCT, AND METHOD FOR PRODUCING EPOXY RESIN CURED PRODUCT 三菱電機株式会社 2021-08-19 WO disclosed
CN-110540608-A Method for preparing hydrogenated diene based nanoemulsions and use of gemini surfactants WANG HUI 2019-12-06 CN disclosed
CN-110078676-A The manufacturing method of alkynyl ketone derivatives 盐野义制药株式会社 2019-08-02 CN disclosed
CN-106488902-B Method for producing alkynyl ketone derivative 盐野义制药株式会社 2019-05-31 CN disclosed
EP-3411217-A1 THREE-DIMENSIONAL INKJET PRINTING USING RING-OPENING METATHESIS POLYMERIZATION Stratasys Ltd. (IL) 2018-12-12 EP disclosed
EP-3411216-A1 DIGITALLY-CONTROLLED THREE-DIMENSIONAL PRINTING USING RING- OPENING METATHESIS POLYMERIZATION Stratasys Ltd. (IL) 2018-12-12 EP disclosed
EP-3107521-A1 ADHESIVE BONDING COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
CN-105504186-A Preparing method and application of 3,4-bi(4-cyanophenyl)-2,5-diphenyl phenyl grafted polysiloxane UNIV SHANDONG 2016-04-20 CN disclosed
WO-2015126865-A1 ADHESIVE BONDING COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-08-27 WO disclosed
US-20080280876-A1 Novel oxadiazole compounds ABBVIE INC. 2008-11-13 US disclosed
US-6323348-B1 CONVERTING ACETOXY-2-CYCLOALKEN-1-OL INTO 4-BENZOYLOXY-2-CYCLOALKEN-1-O1 DERIVATIVE IN PRESENCE OF TRANSITION METAL; CYCLIZATION TO FORM CYCLOALKYL(B)BENZOFURAN DERIVATIVE TORAY INDUSTRIES, INC. (JP) 2001-11-27 US disclosed
CN-1052001-C The preparation of astaxanthin, novel intermediates therefor and the preparation thereof BASF AG (DE) 2000-05-03 CN disclosed
EP-0985669-A1 PROCESS FOR PRODUCING CYCLOALKYL b]BENZOFURANS TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
CN-1098101-A The preparation of astaxanthin, prepare it new intermediate with and preparation BASF AG (DE) 1995-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280876-A1 Novel oxadiazole compounds S1PR3, S1PR1, S1PR2 TDP1 2946/4885CYP3A4 4188/4885ESR1 3158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.