SCHEMBL5028994

SCHEMBL5028994

CCOC(=O)NC=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4852762 0.80 GAA (0.48)
SCHEMBL4852756 0.80 GAA (0.48)
SCHEMBL1416320 0.78
SCHEMBL1416612 0.78
SCHEMBL1555583 0.78
SCHEMBL28547785 0.76
SCHEMBL9681828 0.76 GAA (0.44)
SCHEMBL4076771 0.76
SCHEMBL35709 0.76
SCHEMBL9681835 0.76 GAA (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239841-A1 New compounds BIOVITRUM AB (SE) 2005-10-27 US claimed
WO-2005051381-A1 Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) BIOVITRUM AB (SE) 2005-06-09 WO claimed
US-5723409-A Intermediates for the preparation of phenylsulfonylurea herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-03-03 US claimed
US-5449812-A Substituted benzenesulfonamide derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-12 US claimed
EP-0133349-B1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1988-09-21 EP claimed
US-4652303-A Herbicidal 5-(acylphenyl)cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1987-03-24 US claimed
EP-0133349-A1 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1985-02-20 EP claimed
US-20260001970-A1 HIGH REFRACTIVE INDEX ADHESIVE FORMULATIONS FOR USE IN LASER AMPLIFIER CLADDING L LIVERMORE NAT SECURITY LLC (US) 2026-01-01 US disclosed
CN-109311878-B Triazolopyridines as gamma-secretase modulators 豪夫迈·罗氏有限公司 2022-05-24 CN disclosed
WO-2021116178-A1 PYRAZOLOTRIAZINES BAYER AKTIENGESELLSCHAFT (DE) 2021-06-17 WO disclosed
US-9745274-B2 Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) 2017-08-29 US disclosed
US-9745274-B2 Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) 2017-08-29 US disclosed
US-20160333011-A1 TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS GENENTECH, INC. (US) 2016-11-17 US disclosed
US-20050239841-A1 New compounds BIOVITRUM AB (SE) 2005-10-27 US disclosed
WO-2005051381-A1 Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) BIOVITRUM AB (SE) 2005-06-09 WO disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
EP-0133349-B1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1988-09-21 EP disclosed
US-4652303-A Herbicidal 5-(acylphenyl)cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1987-03-24 US disclosed
EP-0133349-A1 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1985-02-20 EP disclosed
US-4369325-A ANTIPHLOGISTIC AND DIURETIC ACTIVITY EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1983-01-18 US disclosed