Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
| ▸ | ENO1 | P06733 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029046 | 0.89 | GALR1 (0.41) | GALR1ENO1PIK3CAPIK3R1PRKCQ | |
| SCHEMBL5553434 | 0.88 | BCL6 (0.37) | GALR1 | |
| SCHEMBL5036365 | 0.87 | GALR1 (0.55) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL6013860 | 0.87 | GALR1 (0.55) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL6013830 | 0.87 | GALR1 (0.55) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL4836390 | 0.87 | GALR1 (0.55) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL4837841 | 0.87 | GALR1 (0.55) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL4839616 | 0.87 | GALR1 (0.55) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL5029188 | 0.86 | GALR1 (0.53) | GALR1ENO1CDK2CDK1CCNB1 | |
| SCHEMBL4839078 | 0.85 | RPS6KA6 (0.38) | GALR1ENO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332488-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |